Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | C5 | P01031 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31324164 | 0.99 | MEN1 (0.69) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL31324193 | 0.93 | MEN1 (0.73) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL31324199 | 0.91 | MEN1 (0.81) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL10068095 | 0.84 | MAPT (0.69) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| Methane SCHEMBL28656788 | 0.84 | PTGS2 (0.50) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL31324154 | 0.82 | PTGS2 (0.51) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL11018311 | 0.82 | PTGS2 (0.51) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| Methane SCHEMBL8206725 | 0.82 | KDM4E (0.72) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| Methane SCHEMBL28638234 | 0.82 | ALOX15 (0.50) | MEN1MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL11268534 | 0.82 | PTGS2 (0.60) | MEN1MAPTKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102388014-A | Synthesis method of chiral alpha-aryl propionic acid derivative | DSM IP ASSETS BV | 2012-03-21 | — | — | CN | claimed |
| US-20120029226-A1 | METHOD FOR THE SYNTHESIS OF CHIRAL ALPHA-ARYL PROPIONIC ACID DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2012-02-02 | — | — | US | claimed |
| EP-0970694-B1 | Use of carprofen and derivatives therof for treating or preventing articular degeneration | PFIZER PROD INC (US) | 2006-07-05 | — | — | EP | claimed |
| WO-2006042381-A1 | ANTI-INFLAMMATORY PREPARATION | PARNELL LABORATORIES (AUST) PTY LIMITED (AU) | 2006-04-27 | — | — | WO | claimed |
| US-20030212123-A1 | COX-2 selective carprofen for treating pain and inflammation in dogs | PFIZER INC. | 2003-11-13 | — | — | US | claimed |
| US-6506785-B2 | Establishing the status of the mammal as presently or prospectively being in early stages of degeneration of articular cartilage or subchondral bone in one or more joinsts, administering a xanthine chondroprotective compound | PFIZER, INC. | 2003-01-14 | — | — | US | claimed |
| US-20030008911-A1 | Treating or preventing the early stages of degeneration of articular cartilage or subchondral bone in mammals using carprofen and derivatives | EVANS NIGEL A (US) | 2003-01-09 | — | — | US | claimed |
| US-20010002401-A1 | TREATING OR PREVENTING THE EARLY STAGES OF DEGENERATION OF ARTICULAR CARTILAGE OR SUBCHONDRAL BONE IN MAMMALS USING CARPROFEN AND DERIVATIVES | PFIZER INC. | 2001-05-31 | — | — | US | claimed |
| CN-1255059-A | COX-2 selective carprofen for treating pain and inflammation in dogs | PFIZER (US) | 2000-05-31 | — | — | CN | claimed |
| EP-0988034-A1 | COX-2 SELECTIVE CARPROFEN FOR TREATING PAIN AND INFLAMMATION IN DOGS | PFIZER INC. (US) | 2000-03-29 | — | — | EP | claimed |
| EP-0970694-A2 | Use of carprofen and derivatives therof for treating or preventing articular degeneration | Pfizer Products Inc. (US) | 2000-01-12 | — | — | EP | claimed |
| WO-1998050033-A1 | COX-2 SELECTIVE CARPROFEN FOR TREATING PAIN AND INFLAMMATION IN DOGS | PFIZER INC. (US) | 1998-11-12 | — | — | WO | claimed |
| CN-86103879-A | Provide the method for 2-arylpropionic acid for oneself | — | 1987-04-08 | — | — | CN | claimed |
| WO-2025029805-A2 | HEMOSTATIC COMPOSITIONS AND METHODS | PMIDG, LLC (US) | 2025-02-06 | — | — | WO | disclosed |
| CN-111808011-B | High penetration composition and its application | 泰飞尔生物医药(苏州)有限公司 | 2024-02-27 | — | — | CN | disclosed |
| WO-2024030437-A1 | FUNCTIONALIZED AND CROSSLINKED POLYMER METHODS AND COMPOSITIONS | PMIDG, LLC (US) | 2024-02-08 | — | — | WO | disclosed |
| EP-0110671-A1 | Preparation of optically active alpha-arylalkanoic acids and precursors thereof | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1984-06-13 | — | — | EP | disclosed |
| EP-0081993-A2 | Optically active alpha-substituted aryl ketones, their preparation and their use in preparing alpha-arylalkanoic acids | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1983-06-22 | — | — | EP | disclosed |
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |
| EP-0064394-A1 | Manufacture of alpha-arylalkanoic acids and precursors | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1982-11-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212123-A1 | COX-2 selective carprofen for treating pain and inflammation in dogs | PTGES2, PTGER2, PTGS2 | MEN1 4733/4885MAPT 4380/4885KMT2A 1486/4885 |
| US-20010002401-A1 | TREATING OR PREVENTING THE EARLY STAGES OF DEGENERATION OF ARTICULAR CARTILAGE OR SUBCHONDRAL BONE IN MAMMALS USING CARPROFEN AND DERIVATIVES | IGFBP1, IGFBP5, MMP1 | MEN1 4522/4885MAPT 4791/4885KMT2A 4719/4885 |
| US-20030008911-A1 | Treating or preventing the early stages of degeneration of articular cartilage or subchondral bone in mammals using carprofen and derivatives | IGFBP1, MMP1, IGFBP5 | MEN1 4610/4885MAPT 4832/4885KMT2A 4651/4885 |
| US-20120029226-A1 | METHOD FOR THE SYNTHESIS OF CHIRAL ALPHA-ARYL PROPIONIC ACID DERIVATIVES | GRIA1, GRIA3, GRIA2 | MEN1 3864/4885MAPT 2292/4885KMT2A 3494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.