Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29933483 | 0.87 | KDM4E (0.52) | KDM4EHTTPTPN1MAOBKMT2A | |
| SCHEMBL6614160 | 0.87 | KDM4E (0.52) | KDM4EHTTPTPN1MAOBKMT2A | |
| SCHEMBL4576015 | 0.83 | MAOB (0.61) | KDM4EHTTPTPN1MAOBKMT2A | |
| SCHEMBL11262567 | 0.81 | ALDH1A1 (0.48) | KDM4EHTTPTPN1MAOBKMT2A | |
| SCHEMBL11258849 | 0.81 | MAOB (0.51) | KDM4EMAOBKMT2ACSNK2A1ALDH1A1 | |
| SCHEMBL31652614 | 0.79 | HTT (0.48) | KDM4EHTTPTPN1MAOBKMT2A | |
| SCHEMBL11260728 | 0.78 | ALDH1A1 (0.65) | KDM4EHTTMAOBKMT2AMEN1 | |
| SCHEMBL23359886 | 0.77 | KEAP1 (0.46) | KDM4EHTTPTPN1MAOBKMT2A | |
| SCHEMBL11253210 | 0.77 | MAOB (0.67) | MAOBRAB9A | |
| SCHEMBL11255991 | 0.76 | KDM4E (0.37) | KDM4EHTTPTPN1MAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320133-A | Penicillins and their antibacterial use | SANDOZ LTD. (CH) | 1982-03-16 | — | — | US | disclosed |
| EP-0003115-A1 | Penicillins, per se and for use as antibacterially active antibiotics and their production | SANDOZ AG (CH) | 1979-07-25 | — | — | EP | disclosed |