Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA3 | P07451 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3375297 | 0.88 | ALDH1A1 (0.77) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL29933548 | 0.88 | ALDH1A1 (0.77) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL6720375 | 0.84 | MAOB (0.69) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11258849 | 0.81 | MAOB (0.51) | ALDH1A1RAB9AKMT2ASMN1; SMN2HPGD | |
| SCHEMBL12433977 | 0.79 | CA12 (0.64) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL4130899 | 0.79 | ALDH1A1 (1.00) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11268698 | 0.78 | KDM4E (0.48) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11262567 | 0.78 | ALDH1A1 (0.48) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11260734 | 0.77 | MAOB (0.64) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL16541098 | 0.76 | RAB9A (1.00) | ALDH1A1RAB9AKMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320133-A | Penicillins and their antibacterial use | SANDOZ LTD. (CH) | 1982-03-16 | — | — | US | disclosed |
| EP-0003115-A1 | Penicillins, per se and for use as antibacterially active antibiotics and their production | SANDOZ AG (CH) | 1979-07-25 | — | — | EP | disclosed |