SCHEMBL1126876

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL942108	0.82	HTT (0.52)	MAPTKMT2AMEN1RAB9AALDH1A1
	SCHEMBL1987466	0.81	F2 (0.40)	MAPTKMT2AMEN1ALDH1A1GAA
	SCHEMBL941923	0.80	MAPT (0.53)	MAPTKMT2AMEN1RAB9AALDH1A1
	SCHEMBL1646967	0.78	MAPT (0.56)	MAPTKMT2AMEN1ALDH1A1GAA
	SCHEMBL1647801	0.76	MAPT (0.50)	MAPTKMT2AMEN1RAB9AALDH1A1
	SCHEMBL1993805	0.75	MAPT (0.45)	MAPTKMT2AMEN1RAB9AALDH1A1
	SCHEMBL10805478	0.73	MAPT (0.58)	MAPTKMT2AMEN1RAB9AALDH1A1
	SCHEMBL3921914	0.72	MAPT (0.61)	MAPTKMT2AMEN1RAB9AALDH1A1
	SCHEMBL4951791	0.72	MAPT (0.56)	MAPTKMT2AMEN1RAB9AALDH1A1
	SCHEMBL1645593	0.71	DRD2 (0.52)	MAPTKMT2AMEN1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.