Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.67 |
| ▸ | HTR6 | P50406 | 3/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281669 | 0.81 | TAAR1 (0.56) | HTR2A | |
| SCHEMBL31331983 | 0.80 | HTR2A (1.00) | HTR2AHTR6MTNR1AMTNR1BHTR1A | |
| SCHEMBL8021734 | 0.80 | HTR2A (1.00) | HTR2AHTR6MTNR1AMTNR1BHTR1A | |
| Hydrochloric Acid SCHEMBL8573356 | 0.79 | HTR2A (0.97) | HTR2AHTR6MTNR1AMTNR1BHTR1A | |
| SCHEMBL27367183 | 0.79 | HTR6 (0.61) | HTR2AHTR6HTR1AHTR7 | |
| SCHEMBL27365914 | 0.78 | HTR2A (0.61) | HTR2AHTR6NOS1HTR1AHTR7 | |
| SCHEMBL31331965 | 0.78 | HTR2A (0.61) | HTR2AHTR6NOS1HTR1AHTR7 | |
| SCHEMBL3277177 | 0.77 | KDM4E (0.47) | — | |
| SCHEMBL11271603 | 0.77 | KDM4E (0.47) | MTNR1ATDP1 | |
| SCHEMBL8359794 | 0.77 | PDE4A (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |