SCHEMBL31331965

SCHEMBL31331965

COc1cccc2cccc(CCN(C)C)c12

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 5/20 0.61
HTR6 P50406 4/20 0.60
AOC3 Q16853 1/20 0.50
HTR7 P34969 3/20 0.48
HTR1A P08908 2/20 0.48
NOS1 P29475 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27365914 1.00 HTR2A (0.61) HTR2AHTR6AOC3HTR7HTR1A
SCHEMBL27366013 0.86 HTR2A (0.64) HTR2AHTR6AOC3
SCHEMBL27366100 0.84 HTR2A (0.65) HTR2AHTR6AOC3
SCHEMBL27366016 0.84 HTR2A (0.51) HTR2AHTR6AOC3
SCHEMBL31332123 0.84 HTR2A (0.65) HTR2AHTR6AOC3
SCHEMBL31332020 0.84 HTR2A (0.51) HTR2AHTR6AOC3
SCHEMBL27366009 0.84 BCHE (0.48) HTR2AHTR6AOC3HTR7HTR1A
SCHEMBL31332092 0.83 BCHE (0.49) HTR2AAOC3HTR7HTR1A
SCHEMBL27366592 0.83 BCHE (0.49) HTR2AAOC3HTR7HTR1A
SCHEMBL27366601 0.83 HTR2A (0.48) HTR2AHTR6AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333371-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-10-30 US disclosed
EP-4532462-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-04-09 EP disclosed
CN-119384406-A Compounds of formula (I) 赛洛私人有限公司 2025-01-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250333371-A1 COMPOUNDS SDHA, PYGB, SLC18A2 HTR2A 225/4885HTR6 187/4885AOC3 703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.