Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8145067 | 0.78 | DRD3 (0.42) | DRD3DRD2SIGMAR1 | |
| SCHEMBL10676263 | 0.78 | DRD3 (0.42) | DRD3DRD2SIGMAR1 | |
| SCHEMBL10561791 | 0.76 | KDM4E (0.46) | DRD3DRD2 | |
| SCHEMBL4056755 | 0.76 | DRD3 (0.41) | DRD3DRD2SIGMAR1PARP1SLC6A11 | |
| SCHEMBL18957402 | 0.76 | DRD3 (0.41) | DRD3DRD2SIGMAR1 | |
| SCHEMBL10827721 | 0.76 | DRD3 (0.41) | DRD3DRD2SIGMAR1 | |
| SCHEMBL19258960 | 0.76 | KDM4E (0.46) | DRD3DRD2 | |
| SCHEMBL4056759 | 0.76 | ALDH1A1 (0.46) | DRD3DRD2SIGMAR1 | |
| SCHEMBL10827716 | 0.76 | DRD3 (0.41) | DRD3DRD2SIGMAR1SLC6A11 | |
| Methane SCHEMBL2676356 | 0.74 | ALDH1A1 (0.45) | DRD3DRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321387-A | Process for the preparation of optically active nicotine analogs | PHILIP MORRIS, INCORPORATED (US) | 1982-03-23 | — | — | US | disclosed |