Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056759 | 0.98 | ALDH1A1 (0.46) | ALDH1A1KDM4EDRD2DRD3POLB | |
| Nitric Acid SCHEMBL10593117 | 0.87 | ALDH1A1 (0.39) | ALDH1A1KDM4EDRD2DRD3POLB | |
| SCHEMBL16901706 | 0.86 | — | — | |
| SCHEMBL7598071 | 0.86 | — | — | |
| SCHEMBL9327567 | 0.82 | DRD2 (0.35) | ALDH1A1KDM4EDRD2DRD3TSHR | |
| SCHEMBL2201200 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4EPOLBTSHRHPGD | |
| SCHEMBL6992693 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4EPOLBTSHRHPGD | |
| Methane SCHEMBL2678821 | 0.77 | CYP1A2 (0.45) | DRD2DRD3SIGMAR1 | |
| SCHEMBL2297832 | 0.77 | — | — | |
| SCHEMBL10676263 | 0.76 | DRD3 (0.42) | KDM4EDRD2DRD3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120107854-A1 | REAGENT FOR MEASUREMENT OF CHOLINESTERASE ACTIVITY | NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES (JP) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107854-A1 | REAGENT FOR MEASUREMENT OF CHOLINESTERASE ACTIVITY | BCHE, ACHE, SMPD1 | ALDH1A1 660/4885KDM4E 779/4885DRD2 2426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.