Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL2676356 | 0.98 | ALDH1A1 (0.45) | ALDH1A1KDM4EDRD2DRD3POLB | |
| Nitric Acid SCHEMBL10593117 | 0.88 | ALDH1A1 (0.39) | ALDH1A1KDM4EDRD2DRD3POLB | |
| SCHEMBL7598071 | 0.88 | — | — | |
| SCHEMBL16901706 | 0.88 | — | — | |
| SCHEMBL9327567 | 0.84 | DRD2 (0.35) | ALDH1A1KDM4EDRD2DRD3TSHR | |
| SCHEMBL6992693 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KDM4EPOLBTSHRHPGD | |
| SCHEMBL2201200 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KDM4EPOLBTSHRHPGD | |
| SCHEMBL2297832 | 0.78 | — | — | |
| SCHEMBL10676263 | 0.78 | DRD3 (0.42) | KDM4EDRD2DRD3SIGMAR1 | |
| SCHEMBL8145067 | 0.78 | DRD3 (0.42) | DRD2DRD3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11136434-B2 | Polyamines, synthesis method thereof and use thereof for the selective elimination of H2S from a gaseous effluent comprising CO2 | IFP Energies Nouvelles (FR) | 2021-10-05 | — | — | US | claimed |
| CN-108602952-B | Novel polyamines, method for their synthesis and their use for the removal of CO from a gas containing atmosphere2Selective removal of H from the gaseous effluent of2Use of S | IFP 新能源公司 | 2021-03-12 | — | — | CN | claimed |
| US-10710021-B2 | Polyamines, synthesis process thereof and use of same for the selective elimination of H2S from a gaseous effluent comprising CO2 | IFP Energies Nouvelles (FR) | 2020-07-14 | — | — | US | claimed |
| US-20200148824-A1 | NOVEL POLYAMINES, SYNTHESIS METHOD THEREOF AND USE THEREOF FOR THE SELECTIVE ELIMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING CO2 | IFP Energies Nouvelles (FR) | 2020-05-14 | — | — | US | claimed |
| EP-3645605-A1 | NOVEL POLYAMINES, SYNTHESIS METHOD THEREOF AND USE THEREOF FOR THE SELECTIVE ELEMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING C02 | IFP Energies nouvelles (FR) | 2020-05-06 | — | — | EP | claimed |
| EP-3397671-B1 | NOVEL POLYAMINES, SYNTHESIS PROCESS THEREOF AND USE OF SAME FOR THE SELECTIVE ELIMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING CO2 | IFP ENERGIES NOW (FR) | 2020-02-12 | — | — | EP | claimed |
| US-20180369743-A1 | NOVEL POLYAMINES, SYNTHESIS PROCESS THEREOF AND USE OF SAME FOR THE SELECTIVE ELIMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING CO2 | IFP Energies Nouvelles (FR) | 2018-12-27 | — | — | US | claimed |
| WO-2018224350-A1 | NOVEL POLYAMINES, SYNTHESIS METHOD THEREOF AND USE THEREOF FOR THE SELECTIVE ELIMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING CO2 | IFP Energies Nouvelles (FR) | 2018-12-13 | — | — | WO | claimed |
| EP-3397671-A1 | NOVEL POLYAMINES, SYNTHESIS PROCESS THEREOF AND USE OF SAME FOR THE SELECTIVE ELIMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING CO2 | IFP Energies nouvelles (FR) | 2018-11-07 | — | — | EP | claimed |
| WO-2017097716-A1 | NOVEL POLYAMINES, SYNTHESIS PROCESS THEREOF AND USE OF SAME FOR THE SELECTIVE ELIMINATION OF H2S FROM A GASEOUS EFFLUENT COMPRISING CO2 | IFP Energies Nouvelles (FR) | 2017-06-15 | — | — | WO | claimed |
| WO-2016142126-A1 | NOVEL TERTIARY POLYETHER ALKANOLAMINES, METHOD FOR SYNTHESIS THEREOF, AND USE OF SAME FOR THE SELECTIVE REMOVAL OF THE HYDROGEN SULPHIDE FROM A GAS EFFLUENT COMPRISING CARBON DIOXIDE | IFP Energies Nouvelles (FR) | 2016-09-15 | — | — | WO | claimed |
| WO-2016142125-A1 | ABSORBENT SOLUTION BASED ON AMINES COMPRISING A TERTIARY POLYETHERALKANOLAMINE, AND PROCESS FOR SELECTIVE ELIMINATION OF HYDROGEN SULPHIDE FROM A GASEOUS EFFLUENT COMPRISING CARBON DIOXIDE | IFP Energies Nouvelles (FR) | 2016-09-15 | — | — | WO | claimed |
| US-20150314230-A1 | ABSORBENT SOLUTION BASED ON AMINES BELONGING TO THE N-ALKYLHYDROXYPIPERIDINE FAMILY AND METHOD FOR REMOVING ACID COMPOUNDS FROM A GASEOUS EFFLUENT WITH SUCH A SOLUTION | IFP ENGERGIES NOUVELLES (FR) | 2015-11-05 | — | — | US | claimed |
| EP-2928582-A1 | ABSORBENT SOLUTION MADE FROM AMINES BELONGING TO THE N-ALKYL-HYDROXYPIPERIDINE FAMILY AND METHOD FOR ELIMINATING ACID COMPOUNDS FROM A GASEOUS EFFLUENT WITH SUCH A SOLUTION | IFP Energies nouvelles (FR) | 2015-10-14 | — | — | EP | claimed |
| WO-2014087075-A1 | ABSORBENT SOLUTION MADE FROM AMINES BELONGING TO THE N-ALKYL-HYDROXYPIPERIDINE FAMILY AND METHOD FOR ELIMINATING ACID COMPOUNDS FROM A GASEOUS EFFLUENT WITH SUCH A SOLUTION | IFP Energies Nouvelles (FR) | 2014-06-12 | — | — | WO | claimed |
| US-4618599-A | WATER SOLUBILITY | RHONE-POULENC SANTE (FR) | 1986-10-21 | — | — | US | claimed |
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | disclosed |
| US-11136434-B2 | Polyamines, synthesis method thereof and use thereof for the selective elimination of H2S from a gaseous effluent comprising CO2 | IFP Energies Nouvelles (FR) | 2021-10-05 | — | — | US | disclosed |
| US-20080188474-A1 | e.g. 1-phenyl-N3-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-1H-1,2,4-triazole-3,5-diamine; receptor protein tyrosine kinase (AXL) antagonist; antiinflammatory, anticarcinogenic , antidiabetic agent; rheumatoid arthritis, vascular disease; breast, renal, endometrial, ovarian carcinoma, or myeloid leukemia | RIGEL PHARMACEUTICALS, INC. (US) | 2008-08-07 | — | — | US | disclosed |
| WO-2008083356-A1 | SUBSTITUTED TRIAZOLES USEFUL AS AXL INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2008-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188474-A1 | e.g. 1-phenyl-N3-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-1H-1,2,4-triazole-3,5-diamine; receptor protein tyrosine kinase (AXL) antagonist; antiinflammatory, anticarcinogenic , antidiabetic agent; rheumatoid arthritis, vascular disease; breast, renal, endometrial, ovarian carcinoma, or myeloid leukemia | AXL, TYRO3, FLT3 | ALDH1A1 2732/4885KDM4E 1183/4885DRD2 1716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.