Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13312080 | 0.83 | HRH3 (0.36) | HRH3 | |
| Hydrochloric Acid SCHEMBL3498939 | 0.82 | HRH3 (0.35) | HRH3 | |
| SCHEMBL13312090 | 0.82 | HRH3 (0.33) | HRH3 | |
| Hydrochloric Acid SCHEMBL3497187 | 0.81 | HRH3 (0.33) | HRH3 | |
| SCHEMBL11245134 | 0.79 | HTR1A (0.37) | — | |
| SCHEMBL11261606 | 0.78 | HTR1A (0.36) | — | |
| SCHEMBL6946137 | 0.72 | CHRM2 (0.31) | — | |
| SCHEMBL11249497 | 0.72 | HTR7 (0.39) | POLB | |
| SCHEMBL20423696 | 0.69 | CRBN (0.50) | — | |
| SCHEMBL6971705 | 0.69 | HTR7 (0.35) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309541-A | CHEMICAL INTERMEDIATES TO QUINAZOLINE HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |
| US-4255429-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| EP-0009465-A1 | N-(1-(4-amino-2-quinazolinyl)-3 or 4-piperidyl lactames, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1980-04-02 | — | — | EP | disclosed |