Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CASP7 | P55210 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11272245 | 0.94 | PMP22 (0.61) | ADRB2HIF1ATSHRCYP1A2CYP2D6 | |
| Colterol SCHEMBL249585 | 0.81 | ADRB2 (0.72) | ADRB2HIF1ATSHRCYP1A2CYP2D6 | |
| Colterol SCHEMBL3207818 | 0.81 | ADRB2 (0.72) | ADRB2HIF1ATSHRCYP1A2CYP2D6 | |
| Colterol SCHEMBL3220142 | 0.81 | ADRB2 (0.72) | ADRB2HIF1ATSHRCYP1A2CYP2D6 | |
| Acetic Acid SCHEMBL10651198 | 0.79 | ADRB2 (0.62) | ADRB2ADRB1ADRB3 | |
| SCHEMBL11272250 | 0.78 | PMP22 (0.41) | ADRB2HIF1ATSHRCYP1A2CYP2D6 | |
| SCHEMBL11190020 | 0.78 | TDP1 (0.59) | ADRB2HIF1ATSHRCYP1A2CYP2D6 | |
| SCHEMBL6711726 | 0.78 | ADRB2 (0.68) | ADRB2HIF1ATSHRCYP1A2CYP2D6 | |
| SCHEMBL30438779 | 0.78 | ADRB2 (0.68) | ADRB2HIF1ATSHRCYP1A2CYP2D6 | |
| Acetic Acid SCHEMBL10653415 | 0.78 | ADRB2 (0.49) | ADRB2HIF1ACYP1A2CYP2D6ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327224-A | ADRENERGIC BLOCKING AGENTS | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | claimed |