Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.59 |
| ▸ | BLM | P54132 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | RECQL | P46063 | 4/20 | 0.59 |
| ▸ | APEX1 | P27695 | 4/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11192104 | 0.93 | BLM (0.54) | TDP1BLMMAPTKDM4ERECQL | |
| SCHEMBL11372987 | 0.79 | BLM (0.38) | TDP1BLMMAPTKDM4ERECQL | |
| SCHEMBL11268911 | 0.78 | ADRB2 (0.60) | TDP1BLMMAPTKDM4ERECQL | |
| SCHEMBL11192109 | 0.76 | GAA (0.34) | TDP1BLMMAPTKDM4ERECQL | |
| SCHEMBL11192107 | 0.76 | NFKB1 (0.43) | TDP1BLMMAPTKDM4ERECQL | |
| Norepinephrine SCHEMBL2429869 | 0.75 | TDP1 (1.00) | TDP1BLMMAPTKDM4ERECQL | |
| Norepinephrine SCHEMBL2609 | 0.75 | TDP1 (1.00) | TDP1BLMMAPTKDM4ERECQL | |
| L-Norepinephrine SCHEMBL3489077 | 0.75 | TDP1 (1.00) | TDP1BLMMAPTKDM4ERECQL | |
| L-Norepinephrine SCHEMBL29460319 | 0.75 | TDP1 (1.00) | TDP1BLMMAPTKDM4ERECQL | |
| L-Norepinephrine SCHEMBL29371849 | 0.75 | TDP1 (1.00) | TDP1BLMMAPTKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379166-A | Arylmethoxy-, arylmethylthio-, heteroarylmethoxy-, and heteroarylmethylthio-alkylaminoalcohols | SCHERING CORPORATION (US) | 1983-04-05 | — | — | US | disclosed |