Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ERN1 | O75460 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29708012 | 0.82 | TDP1 (0.57) | ALDH1A1ERN1TDP1TSHRHPRT1 | |
| SCHEMBL2030842 | 0.82 | TDP1 (0.57) | ALDH1A1ERN1TDP1TSHRHPRT1 | |
| SCHEMBL984194 | 0.82 | KMT2A (0.50) | ALDH1A1MEN1KMT2AERN1TDP1 | |
| SCHEMBL11284187 | 0.80 | ERN1 (0.56) | ALDH1A1MEN1RAB9AKMT2AERN1 | |
| SCHEMBL3164372 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MEN1RAB9AKMT2AERN1 | |
| SCHEMBL11058082 | 0.76 | CTSB (0.68) | ALDH1A1MEN1RAB9AKMT2ATDP1 | |
| SCHEMBL11436046 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MEN1RAB9AKMT2ATDP1 | |
| SCHEMBL9763412 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AERN1TDP1 | |
| SCHEMBL579426 | 0.73 | ALDH1A1 (0.68) | ALDH1A1MEN1RAB9AKMT2ATDP1 | |
| SCHEMBL30696914 | 0.73 | ALDH1A1 (0.68) | ALDH1A1MEN1RAB9AKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344956-A | Oxotetrahydrothiophenes | ERCOLI NICOLO | 1982-08-17 | — | — | US | disclosed |