Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CLK1 | P49759 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256488 | 0.87 | ALDH1A1 (0.53) | KMT2ALMNAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11268003 | 0.85 | CLK1 (0.48) | KMT2ALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL11265296 | 0.84 | TERT (0.48) | KMT2ALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL11272891 | 0.83 | CSNK1D (0.48) | KMT2ALMNAALDH1A1KDM4EHPGD | |
| SCHEMBL11269478 | 0.82 | EGFR (0.47) | KMT2AALDH1A1KDM4ESMN1; SMN2RECQL | |
| SCHEMBL11266555 | 0.81 | ALDH1A1 (0.48) | KMT2ALMNAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11265331 | 0.80 | KDM4E (0.62) | KMT2AALDH1A1KDM4ESMN1; SMN2POLB | |
| SCHEMBL11256985 | 0.80 | CLK1 (0.57) | KMT2AALDH1A1SMN1; SMN2POLBCLK1 | |
| SCHEMBL11265935 | 0.79 | KDM4E (0.64) | KMT2AALDH1A1KDM4ESMN1; SMN2POLB | |
| SCHEMBL11262482 | 0.79 | KDM4E (0.64) | KMT2AALDH1A1KDM4ESMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |