Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | CLK1 | P49759 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPY4R | P50391 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256488 | 0.83 | ALDH1A1 (0.53) | KDM4ECLK1ALDH1A1TSHRNPY4R | |
| SCHEMBL11269060 | 0.82 | KMT2A (0.51) | KDM4ECLK1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL11252930 | 0.80 | CLK1 (0.41) | KDM4ECLK1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL11268003 | 0.79 | CLK1 (0.48) | KDM4ECLK1ALDH1A1TSHRNPY4R | |
| SCHEMBL11266555 | 0.78 | ALDH1A1 (0.48) | KDM4ECLK1ALDH1A1TSHRNPY4R | |
| SCHEMBL11265296 | 0.78 | TERT (0.48) | KDM4ECLK1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL11272891 | 0.77 | CSNK1D (0.48) | KDM4ECLK1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL11268499 | 0.75 | CLK1 (0.62) | KDM4ECLK1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL11265331 | 0.75 | KDM4E (0.62) | KDM4ECLK1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL11265935 | 0.74 | KDM4E (0.64) | KDM4ECLK1ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |