Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413678 | 0.79 | ALDH1A1 (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL11499500 | 0.76 | KDM4E (0.41) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL29582415 | 0.75 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL9866206 | 0.74 | KDM4E (0.32) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL28618463 | 0.74 | KDM4E (0.32) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL4554901 | 0.71 | KDM4E (0.36) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL28278948 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL20262983 | 0.69 | KDM4E (0.35) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL7323517 | 0.66 | MMP1 (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL16564605 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57146772-A | — | — | None | — | — | JP | disclosed |
| JP-56127377-A | — | — | None | — | — | JP | disclosed |
| JP-56120685-A | — | — | None | — | — | JP | disclosed |
| CN-113227087-A | Macrocyclic compounds and their use in the treatment of disease | 诺华股份有限公司 | 2021-08-06 | — | — | CN | disclosed |
| EP-3283077-A2 | BROMODOMAIN INHIBITOR | Celgene Quanticel Research, Inc. (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168682-A2 | BROMODOMAIN INHIBITOR | CELGENE QUANTICEL RESEARCH, INC. (US) | 2016-10-20 | — | — | WO | disclosed |
| CN-102245636-A | Etoposide and doxorubicin conjugates for drug delivery | ANGIOCHEM INC | 2011-11-16 | — | — | CN | disclosed |
| JP-S57146772-A | 3,3-DI-SUBSTITUTED INDOLIDIN-2-ONE COMPOUND AND ITS PREPARATION | TAIHO YAKUHIN KOGYO KK | 1982-09-10 | — | — | JP | disclosed |
| JP-S56127377-A | 2,3-DIHYDROINDOLIZINE-2-ONE DERIVATIVE AND ITS PREPARATION | TAIHO YAKUHIN KOGYO KK | 1981-10-06 | — | — | JP | disclosed |
| JP-S56120685-A | PYRANO (2,3-B)INDOLIDIN-2-ONE DERIVATIVE AND ITS PREPARATION | TAIHO YAKUHIN KOGYO KK | 1981-09-22 | — | — | JP | disclosed |