Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269500 | 0.74 | KDM4E (0.38) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL11499500 | 0.68 | KDM4E (0.41) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL28278948 | 0.67 | — | — | |
| SCHEMBL7413678 | 0.63 | ALDH1A1 (0.33) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL4554901 | 0.63 | KDM4E (0.36) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL20262983 | 0.61 | KDM4E (0.35) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL16564605 | 0.61 | — | — | |
| SCHEMBL27258731 | 0.60 | KDM4E (0.31) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL28021022 | 0.60 | KDM4E (0.31) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL17261368 | 0.60 | KDM4E (0.30) | KDM4EMEN1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028710-A | Oxidation of corresponding 3-phenylthio indolizine | SANOFI (FR) | 1991-07-02 | — | — | US | claimed |