Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | IL2 | P60568 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9135140 | 0.95 | TRPV1 (0.51) | TRPV1IL2MAPTMEN1KMT2A | |
| SCHEMBL11262471 | 0.94 | TRPV1 (0.52) | TRPV1MAPT | |
| SCHEMBL11261217 | 0.90 | TLR7 (0.46) | TRPV1TLR7GAAL3MBTL1PTGES | |
| SCHEMBL11257811 | 0.85 | TRPV1 (0.48) | TRPV1GAAMAPT | |
| SCHEMBL11271839 | 0.84 | TRPV1 (0.46) | TRPV1MAPTNPSR1TYK2MEN1 | |
| SCHEMBL8660878 | 0.83 | TRPV1 (0.46) | TRPV1IL2MAPTMEN1KMT2A | |
| SCHEMBL11264322 | 0.81 | GAA (0.52) | TRPV1TLR7GAAL3MBTL1PTGES | |
| SCHEMBL11265506 | 0.76 | TRPV1 (0.44) | TRPV1TLR7GAAMAPTNPSR1 | |
| SCHEMBL11258260 | 0.75 | BDKRB1 (0.46) | TRPV1GAAMAPT | |
| SCHEMBL11261749 | 0.74 | RAB9A (0.46) | TRPV1TLR7GAAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336264-A | 1-Benzoyl-3-(isoxazolyl or benzisoxazolyl)-ureas and insecticidal use thereof | ELI LILLY AND COMPANY (US) | 1982-06-22 | — | — | US | claimed |