Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 2/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261217 | 0.94 | TLR7 (0.46) | TRPV1MAPTNPSR1TYK2 | |
| SCHEMBL11262471 | 0.90 | TRPV1 (0.52) | TRPV1MAPT | |
| SCHEMBL11258260 | 0.89 | BDKRB1 (0.46) | TRPV1MAPTSTAT3STAT1RORC | |
| SCHEMBL8660878 | 0.89 | TRPV1 (0.46) | TRPV1MAPTSTAT3STAT1MEN1 | |
| SCHEMBL11269508 | 0.84 | TRPV1 (0.48) | TRPV1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL9135140 | 0.80 | TRPV1 (0.51) | TRPV1MAPTMEN1KMT2A | |
| SCHEMBL11262815 | 0.79 | SMN1; SMN2 (0.49) | TRPV1MAPTRORCMEN1KMT2A | |
| SCHEMBL11257811 | 0.78 | TRPV1 (0.48) | TRPV1MAPTRORC | |
| SCHEMBL11261749 | 0.78 | RAB9A (0.46) | TRPV1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11265506 | 0.77 | TRPV1 (0.44) | TRPV1MAPTSTAT3STAT1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336264-A | 1-Benzoyl-3-(isoxazolyl or benzisoxazolyl)-ureas and insecticidal use thereof | ELI LILLY AND COMPANY (US) | 1982-06-22 | — | — | US | claimed |