SCHEMBL1126969

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127393	0.85	BRD4 (0.50)	BRD4ALDH1A1KDM4EGLAGAA
	SCHEMBL1127035	0.82	BRD4 (0.45)	BRD4ALDH1A1KDM4EGLAGAA
	SCHEMBL1990116	0.76	BRD4 (0.46)	BRD4ALDH1A1KDM4EGLAGAA
	SCHEMBL11878553	0.72	SMN1; SMN2 (0.46)	BRD4ALDH1A1KDM4ETSHRHPGD
	SCHEMBL1126626	0.70	BRD4 (0.60)	BRD4ALDH1A1KDM4EGLAGAA
	SCHEMBL10246572	0.68	CYP11B1 (0.55)	PDE10AHSD11B1MAPTRAB9ATLR8
	Biphenyl SCHEMBL967556	0.67	ALDH1A1 (0.64)	ALDH1A1KDM4ETSHRHPGDSMN1; SMN2
	SCHEMBL17266867	0.67	BRD4 (0.52)	BRD4ALDH1A1KDM4EGLAGAA
	SCHEMBL1126710	0.67	BRD4 (0.52)	BRD4ALDH1A1KDM4EGLAGAA
	SCHEMBL1126929	0.67	TYR (0.46)	BRD4ALDH1A1KDM4EGLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.