Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 5/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541593 | 0.79 | CA12 (0.54) | PNMTADRA2AMAPTMEN1KMT2A | |
| SCHEMBL717841 | 0.78 | PNMT (0.50) | PNMTADRA2AMAPTMEN1KMT2A | |
| SCHEMBL11269163 | 0.77 | MAPT (0.35) | MAPTLMNACA12CA1CA2 | |
| SCHEMBL11267164 | 0.77 | CA12 (0.35) | MAPTRAB9ALMNANPC1CA12 | |
| Hydrochloric Acid SCHEMBL6210737 | 0.77 | PNMT (0.49) | PNMTADRA2AMAPTMEN1KMT2A | |
| SCHEMBL11280879 | 0.77 | AHR (0.36) | PNMTADRA2AMAPTADRA2BADRA2C | |
| SCHEMBL200716 | 0.76 | PNMT (0.58) | PNMTADRA2AMAPTMEN1KMT2A | |
| SCHEMBL27599386 | 0.75 | CA12 (0.50) | PNMTADRA2AMAPTMEN1KMT2A | |
| SCHEMBL11268349 | 0.74 | PNMT (0.43) | PNMTADRA2AMAPTMEN1KMT2A | |
| SCHEMBL11260147 | 0.74 | PNMT (0.36) | PNMTMAPTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | claimed |
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | disclosed |