SCHEMBL200716

SCHEMBL200716

O=[N+]([O-])c1ccc2c(c1)CCN2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 5/20 0.58
ADRA2A P08913 3/20 0.58
MAPT P10636 5/20 0.53
ALDH1A1 P00352 1/20 0.53
SIRT2 Q8IXJ6 1/20 0.52
DRD2 P14416 1/20 0.50
DRD4 P21917 1/20 0.50
CTSL P07711 1/20 0.48
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
LMNA P02545 2/20 0.44
HTT P42858 1/20 0.44
NCOA1 Q15788 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
NCOA3 Q9Y6Q9 1/20 0.44
TDP2 O95551 1/20 0.44
CAPN9 O14815 1/20 0.44
CASP3 P42574 1/20 0.44
ACHE P22303 1/20 0.43
ADRA2B P18089 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL27508397 0.98 PNMT (0.57) PNMTADRA2AMAPTALDH1A1SIRT2
Ammonia Solution, Strong SCHEMBL28209706 0.98 PNMT (0.57) PNMTADRA2AMAPTALDH1A1SIRT2
SCHEMBL27408384 0.95 PNMT (0.54) PNMTADRA2AMAPTALDH1A1SIRT2
Acetaldehyde SCHEMBL27415337 0.92 PNMT (0.51) PNMTADRA2AMAPTALDH1A1SIRT2
Sulfuric Acid SCHEMBL29269875 0.92 PNMT (0.51) PNMTADRA2AMAPTALDH1A1SIRT2
Butane SCHEMBL27459660 0.92 PNMT (0.51) PNMTADRA2AMAPTALDH1A1SIRT2
Pyrimidine SCHEMBL28303381 0.91 ADRA2A (0.50) PNMTADRA2AMAPTALDH1A1SIRT2
Acetic Acid SCHEMBL28007453 0.91 SIRT2 (0.52) PNMTADRA2AMAPTALDH1A1SIRT2
SCHEMBL28171953 0.91 SIRT2 (0.52) PNMTADRA2AMAPTALDH1A1SIRT2
Propene SCHEMBL27474388 0.91 PNMT (0.50) PNMTADRA2AMAPTALDH1A1SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
CN-119463156-A Amphiphilic organic near-infrared thermal activation delayed fluorescence molecule and preparation method and application thereof 内蒙古大学 2025-02-18 CN claimed
CN-117624179-A 3- (amino) methylene indoline derivative and preparation method and application thereof 徐诺药业(南京)有限公司 2024-03-01 CN claimed
WO-2022016690-A1 LUCIFERASE SUBSTRATES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 山东大学 2022-01-27 WO claimed
CN-111675724-A Luciferase substrate and preparation method and application thereof 山东大学 2020-09-18 CN claimed
CN-110168103-A Reduce the method that primer dimer forms and improves amplification efficiency SEEGENE株式会社 2019-08-23 CN claimed
CN-109971845-A A kind of PCR primer group and amplification system expanding mankind PKD1 gene 1-33 exon 阅尔基因技术(苏州)有限公司 2019-07-05 CN claimed
CN-109868309-A Single stranded DNA amplification method based on universal base replacement insertion 厦门市安美捷生物工程有限公司 2019-06-11 CN claimed
CN-109852727-A HBV-cccDNA detection method and kit based on universal base replacement insertion 厦门市安美捷生物工程有限公司 2019-06-07 CN claimed
CN-109825569-A PCR primer group, kit, amplification system and the detection method of gene DPY19L2 exon 阅尔基因技术(苏州)有限公司 2019-05-31 CN claimed
CN-1833034-A Probes, libraries and kits for analysis of mixtures of nucleic acids and methods for constructing the same EXIQON AS (DK) 2006-09-13 CN claimed
CN-1796984-A Technique for generating and enhancing fluorescence signal in use for detection of gene chip GUAN YIFU (CN) 2006-07-05 CN claimed
WO-2006014420-A1 QUINAZOLINE MODULATORS OF HEPATOCYTE GROWTH FACTOR / C-MET ACTIVITY FOR THE TREATMENT OF CANCER ANGION BIOMEDICA CORPORATION (US) 2006-02-09 WO claimed
US-20060025406-A1 Modulators of hepatocyte growth factor/c- Met activity ANGION BIOMEDICA CORPORATION (US) 2006-02-02 US claimed
CN-1602361-A Hybridization portion control oligonucleotide and use thereof SEEGENE INC (KR) 2005-03-30 CN claimed
CN-1578841-A Annealing control primer and use of the same VISION GENE CO LTD (KR) 2005-02-09 CN claimed
CN-1505685-A Method for rapid detection and identification of biological objects ISISҩ��ɷ����޹�˾ 2004-06-16 CN claimed
CN-1085556-A The 4-pyrimidyl and the pyridinyl derivatives of the indol-3-yl alkylpiperazine of anti-migraine BRISTOL MYERS SQUIBB CO (US) 1994-04-20 CN claimed
US-4941996-A CYCLODEXTRINS HOSTS AND AROMATIC COMPOUNDS WITH ELECTRON DONATING AND ELECTRON WITHDRAWING GROUPS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-07-17 US claimed
US-4929392-A CYCLODEXTRINS, NITROINDOLINES, 4-N,N-DIMETHYLAMINOBENZYLIDENE-2-HYDROXY ANILINES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-05-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060025406-A1 Modulators of hepatocyte growth factor/c- Met activity HGF, MET, HDGF PNMT 1212/4885ADRA2A 3249/4885MAPT 3372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.