Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267164 | 0.81 | CA12 (0.35) | AHRCA12CA1CA2CA9 | |
| SCHEMBL11269163 | 0.81 | MAPT (0.35) | CA12CA1CA2CA9DRD4 | |
| SCHEMBL11260147 | 0.79 | PNMT (0.36) | CA12CA1CA2CA9DRD2 | |
| SCHEMBL11262166 | 0.78 | GAA (0.38) | HTR2AHTR2CHTR2BCA12CA1 | |
| SCHEMBL11274713 | 0.78 | PDE3B (0.41) | HTR2CCA12CA1CA2CA9 | |
| SCHEMBL11266164 | 0.77 | ALOX15 (0.36) | CA12CA1CA2CA9MAPT | |
| SCHEMBL11269742 | 0.77 | PNMT (0.41) | CA12CA1CA2CA9ADRA2A | |
| SCHEMBL1091532 | 0.74 | MAPT (0.54) | AHRHTR2AHTR2CHTR2BCA12 | |
| SCHEMBL30839280 | 0.73 | KDM4E (0.49) | AHRHTR2AHTR2CHTR2BCA12 | |
| SCHEMBL10122766 | 0.73 | KDM4E (0.49) | AHRHTR2AHTR2CHTR2BCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | claimed |
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | disclosed |