SCHEMBL11269779

SCHEMBL11269779

OCCn1cnc2c(S)ncnc21

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 8/20 0.66
ADORA1 P30542 3/20 0.66
CYP1A2 P05177 3/20 0.51
CYP2D6 P10635 1/20 0.46
MAPK1 P28482 1/20 0.46
ADORA2B P29275 1/20 0.45
ADCY1 Q08828 1/20 0.45
AHCY P23526 5/20 0.41
TSHR P16473 1/20 0.41
PI4KA P42356 1/20 0.40
PI4K2B Q8TCG2 1/20 0.40
PI4K2A Q9BTU6 1/20 0.40
PI4KB Q9UBF8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8467559 0.87 ADORA2A (0.60) ADORA2AADORA1CYP1A2CYP2D6MAPK1
SCHEMBL10889158 0.81 ADORA2A (0.68) ADORA2AADORA1CYP1A2CYP2D6MAPK1
SCHEMBL2115918 0.80 ADORA2A (0.68) ADORA2AADORA1CYP1A2CYP2D6MAPK1
SCHEMBL10582562 0.80 PNP (0.50) ADORA2AADORA1AHCYTSHR
SCHEMBL28950092 0.79 ADORA2A (0.66) ADORA2AADORA1CYP1A2CYP2D6MAPK1
SCHEMBL984944 0.79 ADORA2A (1.00) ADORA2AADORA1ADORA2BADCY1AHCY
SCHEMBL9741153 0.79 ADORA2A (0.66) ADORA2AADORA1CYP1A2CYP2D6MAPK1
SCHEMBL19242631 0.79 ADORA2A (0.66) ADORA2AADORA1CYP1A2CYP2D6MAPK1
SCHEMBL29459142 0.79 ADORA2A (1.00) ADORA2AADORA1ADORA2BADCY1AHCY
SCHEMBL1082007 0.79 ADORA2A (0.61) ADORA2AADORA1CYP1A2CYP2D6MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111847671-B Bionic pilus honeycomb superstructure and preparation method and application thereof 中国石油大学(北京) 2022-02-08 CN disclosed
CN-111847671-A Bionic pilus honeycomb superstructure and preparation method and application thereof 中国石油大学(北京) 2020-10-30 CN disclosed
EP-0009154-B1 COMPLEXES OF 9-HYDROXYALKYL-PURINES, PROCESSES FOR PREPARING THEM AND THERAPEUTICAL COMPOSITIONS CONTAINING THE COMPLEXES AS ACTIVE INGREDIENTS Newport Pharmaceuticals International, Inc. (US) 1982-12-08 EP disclosed