Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 11/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 11/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261499 | 0.92 | CA12 (0.45) | LMNANPC1RAB9ASMN1; SMN2CA12 | |
| SCHEMBL11533734 | 0.86 | LMNA (0.66) | LMNANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11535620 | 0.86 | LMNA (0.45) | LMNANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11269784 | 0.82 | LMNA (0.68) | LMNACYP11B1CYP11B2CA12CA1 | |
| SCHEMBL11542258 | 0.80 | LMNA (0.46) | LMNANPC1RAB9ASMN1; SMN2CYP11B1 | |
| SCHEMBL11535854 | 0.78 | LMNA (0.74) | LMNACYP11B1CYP11B2CA12CA1 | |
| SCHEMBL11478775 | 0.78 | LMNA (0.61) | LMNANPC1RAB9ASMN1; SMN2CA12 | |
| SCHEMBL11530459 | 0.77 | LMNA (0.48) | LMNANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| Sulbenox SCHEMBL11740934 | 0.77 | SMN1; SMN2 (0.44) | LMNANPC1RAB9ASMN1; SMN2CA12 | |
| Sulbenox SCHEMBL110252 | 0.77 | SMN1; SMN2 (0.44) | LMNANPC1RAB9ASMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150035-A | ANIMAL CROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1979-04-17 | — | — | US | claimed |
| US-4150035-A | ANIMAL CROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1979-04-17 | — | — | US | disclosed |