Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11483687 | 0.87 | LMNA (0.92) | LMNACXCR2KMT2AMEN1EPHX1 | |
| SCHEMBL11484122 | 0.84 | LMNA (0.69) | LMNACXCR2KMT2AMEN1EPHX1 | |
| SCHEMBL11483511 | 0.84 | LMNA (0.69) | LMNACXCR2KMT2AMEN1EPHX1 | |
| SCHEMBL11267633 | 0.84 | LMNA (0.69) | LMNACXCR2KMT2AMEN1EPHX1 | |
| SCHEMBL11261936 | 0.83 | LMNA (0.63) | LMNACXCR2KMT2AMEN1EPHX1 | |
| SCHEMBL11269784 | 0.83 | LMNA (0.68) | LMNACXCR2CCR6 | |
| SCHEMBL11492871 | 0.83 | LMNA (0.67) | LMNACXCR2KMT2AMEN1EPHX1 | |
| SCHEMBL11484018 | 0.83 | LMNA (0.67) | LMNACXCR2KMT2AMEN1EPHX1 | |
| SCHEMBL11534547 | 0.82 | LMNA (1.00) | LMNACXCR2KMT2AMEN1EPHX1 | |
| SCHEMBL11273026 | 0.82 | LMNA (0.62) | LMNACXCR2KMT2AMEN1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156670-A | UREAS AND THIOUREAS, HERBICIDES, ANIMAL GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1979-05-29 | — | — | US | claimed |
| US-4036979-A | ANIMAL GROWTH RATE ACCELERATOR | AMERICAN CYANAMID COMPANY (US) | 1977-07-19 | — | — | US | claimed |
| US-4191830-A | HERBICIDES AND ANIMAL GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1980-03-04 | — | — | US | disclosed |
| US-4156670-A | UREAS AND THIOUREAS, HERBICIDES, ANIMAL GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1979-05-29 | — | — | US | disclosed |
| US-4036979-A | ANIMAL GROWTH RATE ACCELERATOR | AMERICAN CYANAMID COMPANY (US) | 1977-07-19 | — | — | US | disclosed |