Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.51 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269789 | 1.00 | NOX4 (0.51) | NOX4NOX1MGLLKMT2AMEN1 | |
| SCHEMBL11275254 | 0.86 | HSP90AA1 (0.46) | NOX4NOX1MGLLKMT2AMEN1 | |
| SCHEMBL11275245 | 0.86 | HSP90AA1 (0.46) | NOX4NOX1MGLLKMT2AMEN1 | |
| SCHEMBL10509799 | 0.86 | NOX4 (0.49) | NOX4NOX1MGLLKMT2AMEN1 | |
| SCHEMBL11277409 | 0.84 | MEN1 (0.51) | NOX4NOX1MGLLKMT2AMEN1 | |
| SCHEMBL11277401 | 0.84 | MEN1 (0.51) | NOX4NOX1MGLLKMT2AMEN1 | |
| SCHEMBL11277679 | 0.84 | ALDH1A1 (0.49) | NOX4NOX1KMT2AMEN1GAA | |
| SCHEMBL11277684 | 0.84 | ALDH1A1 (0.49) | NOX4NOX1KMT2AMEN1GAA | |
| SCHEMBL11282741 | 0.83 | BCL2A1 (0.52) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL11282746 | 0.83 | BCL2A1 (0.52) | KMT2AMEN1GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4345935-A | PREEMERGENT AND POSTEMERGENT APPLICATION | ELI LILLY AND COMPANY (US) | 1982-08-24 | — | — | US | disclosed |
| US-4345936-A | Imidazoles, compositions and herbicidal method | ELI LILLY AND COMPANY (US) | 1982-08-24 | — | — | US | disclosed |