Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11257095 | 0.98 | HPGD (0.50) | HPGDHTTKDM4EGAASMN1; SMN2 | |
| SCHEMBL5717746 | 0.75 | KDM4E (0.74) | HPGDHTTKDM4EGAASMN1; SMN2 | |
| SCHEMBL7205313 | 0.74 | HPGD (0.64) | HPGDHTTKDM4EGAASMN1; SMN2 | |
| SCHEMBL13768213 | 0.71 | HPGD (0.60) | HPGDHTTKDM4EGAASMN1; SMN2 | |
| SCHEMBL29163011 | 0.71 | HTT (0.60) | HPGDHTTKDM4EGAASMN1; SMN2 | |
| SCHEMBL5717828 | 0.69 | KDM4E (0.61) | HPGDHTTKDM4EGAASMN1; SMN2 | |
| SCHEMBL11882485 | 0.68 | KDM4E (0.52) | HPGDHTTKDM4EGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11673060 | 0.68 | LMNA (0.51) | HPGDGAANPSR1NPC1RAB9A | |
| SCHEMBL30129312 | 0.68 | HPGD (1.00) | HPGDHTTKDM4EGAASMN1; SMN2 | |
| SCHEMBL11262261 | 0.68 | ALDH1A1 (0.45) | HPGDHTTKDM4EGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349674-A | Quinoalinyl esters of carbamimidothioic acids | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-09-14 | — | — | US | disclosed |