Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 4/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | ATP4A | P20648 | 1/20 | 0.37 |
| ▸ | ATP4B | P51164 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267686 | 0.95 | HMOX1 (0.46) | HMOX1NOS1CYP19A1ATP4AATP4B | |
| SCHEMBL11265147 | 0.88 | HMOX1 (0.47) | HMOX1NOS1CYP19A1ATP4AATP4B | |
| SCHEMBL11259920 | 0.88 | HMOX1 (0.47) | HMOX1NOS1 | |
| SCHEMBL11264876 | 0.86 | NOS1 (0.50) | HMOX1NOS1CYP19A1ATP4AATP4B | |
| SCHEMBL11264370 | 0.86 | HMOX1 (0.46) | HMOX1NOS1CYP19A1 | |
| SCHEMBL11262573 | 0.84 | CYP2A6 (0.52) | HMOX1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11264378 | 0.84 | CYP19A1 (0.51) | HMOX1NOS1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11257492 | 0.84 | CYP11B1 (0.51) | HMOX1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11258481 | 0.84 | CYP11B1 (0.49) | CYP19A1TBXAS1CYP11B1CYP11B2 | |
| SCHEMBL11257342 | 0.83 | HMOX1 (0.49) | HMOX1NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |