Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 4/20 | 0.47 |
| ▸ | ATP4A | P20648 | 1/20 | 0.40 |
| ▸ | ATP4B | P51164 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259981 | 0.95 | HMOX1 (0.49) | HMOX1NOS1ATP4AATP4BQPCT | |
| SCHEMBL11264876 | 0.93 | NOS1 (0.50) | HMOX1NOS1ATP4AATP4BQPCT | |
| SCHEMBL11266684 | 0.90 | HMOX1 (0.52) | HMOX1NOS1ATP4AATP4BCYP19A1 | |
| SCHEMBL11254044 | 0.89 | NOS1 (0.52) | HMOX1NOS1ATP4AATP4BQPCT | |
| SCHEMBL11269948 | 0.88 | HMOX1 (0.44) | HMOX1NOS1ATP4AATP4BCYP19A1 | |
| SCHEMBL11273449 | 0.86 | NOS1 (0.47) | HMOX1NOS1ATP4AATP4BQPCT | |
| SCHEMBL11252110 | 0.85 | HMOX1 (0.43) | HMOX1NOS1ATP4AATP4BQPCT | |
| SCHEMBL11253258 | 0.85 | CYP2A6 (0.50) | HMOX1QPCTCYP19A1 | |
| SCHEMBL11269020 | 0.85 | HMOX1 (0.50) | HMOX1NOS1CYP19A1 | |
| SCHEMBL11258631 | 0.85 | CYP11B1 (0.49) | QPCTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |