Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | TLR4 | O00206 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271545 | 0.88 | GABRP (0.51) | PPARGTLR4ALDH1A1LMNAPOLB | |
| SCHEMBL11272884 | 0.85 | PPARG (0.67) | PPARGTLR4ALDH1A1LMNAPOLB | |
| SCHEMBL18928224 | 0.82 | PPARG (0.65) | PPARGTLR4ALDH1A1LMNAPOLB | |
| SCHEMBL18928225 | 0.82 | PPARG (0.68) | PPARGTLR4ALDH1A1LMNAPOLB | |
| SCHEMBL11276567 | 0.82 | PPARG (0.65) | PPARGTLR4ALDH1A1LMNAPOLB | |
| SCHEMBL11636322 | 0.78 | PPARG (0.62) | PPARGTLR4ALDH1A1LMNAPOLB | |
| SCHEMBL11261825 | 0.78 | GABRP (0.51) | PPARGALDH1A1LMNAPOLBKDM4E | |
| SCHEMBL9853488 | 0.76 | MAPT (0.63) | PPARGALDH1A1LMNAPOLBKDM4E | |
| SCHEMBL11223132 | 0.75 | ALDH1A1 (0.45) | ALDH1A1LMNAPOLBKDM4EMAPT | |
| SCHEMBL13603806 | 0.74 | MAPT (0.60) | PPARGALDH1A1LMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004024-B1 | METHOD FOR PREPARING 3-HYDROXY-6-PHENYL-1,2,3,4-TETRAHYDRO-1,5-BENZODIAZOCINES | Kali-Chemie Pharma GmbH (DE) | 1982-02-24 | — | — | EP | disclosed |
| EP-0004024-A2 | Method for preparing 3-hydroxy-6-phenyl-1,2,3,4-tetrahydro-1,5-benzodiazocines | Kali-Chemie Pharma GmbH (DE) | 1979-09-19 | — | — | EP | disclosed |