Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253467 | 1.00 | KMT2A (0.39) | KMT2AMEN1TRPM8MAPTTP53 | |
| SCHEMBL11256894 | 0.99 | KMT2A (0.37) | KMT2AMEN1TRPM8MAPTTP53 | |
| SCHEMBL11265250 | 0.93 | CA12 (0.37) | KMT2AMEN1MAPTTP53NPC1 | |
| SCHEMBL11268012 | 0.88 | CA12 (0.36) | KMT2AMEN1MAPTTP53NPC1 | |
| SCHEMBL11271015 | 0.72 | HTR2C (0.40) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL11270915 | 0.72 | HTR2C (0.40) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL11255745 | 0.71 | HTR2C (0.41) | KMT2AMEN1NPC1RAB9ALMNA | |
| Hydrochloric Acid SCHEMBL11273062 | 0.71 | RAD52 (0.41) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL11255499 | 0.70 | HDAC6 (0.37) | KMT2AMEN1MAPTTP53NPC1 | |
| SCHEMBL11255635 | 0.70 | HTR2C (0.41) | KMT2AMEN1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344946-A | ANTIARTHRITICS, ANTIRHEUMATICS | BOEHRINGER INGELHEIM GMBH (DE) | 1982-08-17 | — | — | US | disclosed |