Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30585634 | 1.00 | MEN1 (0.30) | MEN1LMNAHSP90AA1MAPTHPGD | |
| SCHEMBL30585633 | 1.00 | MEN1 (0.30) | MEN1LMNAHSP90AA1MAPTHPGD | |
| SCHEMBL11052010 | 0.79 | LMNA (0.49) | MEN1LMNAHTTKMT2A | |
| SCHEMBL29065423 | 0.78 | APLNR (0.32) | MAPT | |
| SCHEMBL11140604 | 0.78 | APLNR (0.32) | MAPT | |
| SCHEMBL13845901 | 0.78 | APLNR (0.32) | MAPT | |
| SCHEMBL15978554 | 0.78 | GBA1 (0.30) | — | |
| SCHEMBL29246833 | 0.78 | GBA1 (0.30) | — | |
| SCHEMBL11403725 | 0.76 | — | — | |
| SCHEMBL11315550 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332745-A | Preparation of 2-cyano-3,3-dimethyl-cyclopropane-1-carboxylic acid esters and intermediates therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1982-06-01 | — | — | US | disclosed |
| US-4307033-A | Preparation of 3,3-dimethyl-cyclopropane-1,1,2-tricarboxylic acid derivatives and intermediates therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-22 | — | — | US | disclosed |