Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | PPM1B | O75688 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29246850 | 0.80 | LMNA (0.47) | LMNAALDH1A1TSHRTP53HTT | |
| SCHEMBL8159372 | 0.80 | LMNA (0.47) | LMNAALDH1A1TSHRTP53HTT | |
| SCHEMBL8159369 | 0.80 | LMNA (0.47) | LMNAALDH1A1TSHRTP53HTT | |
| SCHEMBL8081928 | 0.80 | LMNA (0.47) | LMNAALDH1A1TSHRTP53HTT | |
| SCHEMBL9560007 | 0.79 | LMNA (0.46) | LMNAALDH1A1TSHRTP53HTT | |
| SCHEMBL30084108 | 0.79 | LMNA (0.46) | LMNAALDH1A1TSHRTP53HTT | |
| SCHEMBL30084103 | 0.79 | LMNA (0.46) | LMNAALDH1A1TSHRTP53HTT | |
| SCHEMBL11270207 | 0.79 | MEN1 (0.30) | LMNAMEN1KMT2AHTT | |
| SCHEMBL30585633 | 0.79 | MEN1 (0.30) | LMNAMEN1KMT2AHTT | |
| SCHEMBL30585634 | 0.79 | MEN1 (0.30) | LMNAMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448728-A | Preparation of cis ester-nitrile cyclopropane compounds | ROUSSEL UCLAF (FR) | 1984-05-15 | — | — | US | disclosed |
| US-4420435-A | Alpha-hydroxy-phosphonic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1983-12-13 | — | — | US | disclosed |
| EP-0043307-B1 | CYCLOPROPANE-1-CARBOXYLIC ACID DERIVATIVES , THEIR SALTS, THEIR PREPARATION AND USE IN THE SYNTHESIS OF INTERMEDIATES OF CIS-PYRETHROIDS | ROUSSEL-UCLAF (FR) | 1983-11-23 | — | — | EP | disclosed |
| US-4358409-A | Preparation of styryl cyclopropane insecticide intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-09 | — | — | US | disclosed |
| US-4332745-A | Preparation of 2-cyano-3,3-dimethyl-cyclopropane-1-carboxylic acid esters and intermediates therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1982-06-01 | — | — | US | disclosed |
| EP-0043307-A1 | Cyclopropane-1-carboxylic acid derivatives , their salts, their preparation and use in the synthesis of intermediates of cis-pyrethroids | ROUSSEL-UCLAF (FR) | 1982-01-06 | — | — | EP | disclosed |
| US-4307033-A | Preparation of 3,3-dimethyl-cyclopropane-1,1,2-tricarboxylic acid derivatives and intermediates therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1981-12-22 | — | — | US | disclosed |