Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 5/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27797471 | 0.83 | NISCH (0.63) | NISCHMAOBMAOAMAPTHTR1A | |
| Hydrochloric Acid SCHEMBL3060877 | 0.82 | NISCH (0.61) | NISCHMAOBMAOAMAPTHTR1A | |
| SCHEMBL6166678 | 0.78 | HTR1B (0.59) | NISCHMAOBMAOAMAPTADRA2A | |
| SCHEMBL5203987 | 0.78 | NISCH (0.68) | NISCHMAOBMAOAHTR1AADRA2A | |
| SCHEMBL3173653 | 0.78 | NISCH (0.68) | NISCHMAOBMAOAHTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL5827995 | 0.77 | HTR1B (0.58) | NISCHMAOBMAOAMAPTADRA2A | |
| SCHEMBL5827781 | 0.77 | MAOA (0.57) | NISCHMAOBMAOAMAPTADRA2A | |
| SCHEMBL8478297 | 0.77 | NISCH (0.58) | NISCHMAOBMAOAHTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL5201240 | 0.77 | NISCH (0.66) | NISCHMAOBMAOAHTR1AADRA2A | |
| SCHEMBL546875 | 0.77 | NISCH (1.00) | NISCHMAOBMAOAHTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343808-A | Method of inhibiting sickling of sickle erythrocytes | THE DOW CHEMICAL COMPANY (US) | 1982-08-10 | — | — | US | claimed |