Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 6/20 | 0.62 |
| ▸ | POLA1 | P09884 | 1/20 | 0.53 |
| ▸ | PI4KA | P42356 | 1/20 | 0.51 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.51 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.51 |
| ▸ | PNP | P00491 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680703 | 0.94 | XDH (0.60) | XDHPOLA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL28252089 | 0.88 | XDH (0.56) | XDHPOLA1PNPALDH1A1PDE5A | |
| SCHEMBL11133891 | 0.82 | PNP (0.57) | XDHPOLA1PNPALDH1A1PDE5A | |
| SCHEMBL7809886 | 0.78 | XDH (0.57) | XDHPOLA1PNPCDK1CCNB1 | |
| SCHEMBL4384744 | 0.77 | XDH (1.00) | XDHPOLA1 | |
| SCHEMBL8535457 | 0.77 | XDH (1.00) | XDHPOLA1 | |
| SCHEMBL10528232 | 0.76 | XDH (0.60) | XDHPOLA1PNPCDK1CCNB1 | |
| Hydrochloric Acid SCHEMBL258899 | 0.76 | XDH (0.97) | XDHPOLA1 | |
| Guanine SCHEMBL26629010 | 0.76 | PNP (0.67) | XDHPOLA1PNPALDH1A1CDK1 | |
| SCHEMBL3396585 | 0.75 | PNP (0.57) | XDHPNPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009154-B1 | COMPLEXES OF 9-HYDROXYALKYL-PURINES, PROCESSES FOR PREPARING THEM AND THERAPEUTICAL COMPOSITIONS CONTAINING THE COMPLEXES AS ACTIVE INGREDIENTS | Newport Pharmaceuticals International, Inc. (US) | 1982-12-08 | — | — | EP | disclosed |
| US-4221910-A | IMMUNOPOTENTIATORS, VIRICIDES, ANTILEUKEMIA AGENTS | NEWPORT PHARMACEUTICALS INTERNATIONAL, INC. (US) | 1980-09-09 | — | — | US | disclosed |
| US-4221909-A | P-Acetamidobenzoic acid salts of 9-(hydroxyalkyl) purines | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1980-09-09 | — | — | US | disclosed |
| US-4221794-A | Method of imparting immunomodulating and antiviral activity | NEWPORT PHARMACEUTICALS INTERNATIONAL, INC. (US) | 1980-09-09 | — | — | US | disclosed |
| EP-0009155-A1 | 9-Hydroxyalkyl-purines, processes for preparing them and therapeutical composition containing the 9-hydroxyalkyl-purines as active ingredients | Newport Pharmaceuticals International, Inc. (US) | 1980-04-02 | — | — | EP | disclosed |
| EP-0009154-A1 | Complexes of 9-hydroxyalkyl-purines, processes for preparing them and therapeutical compositions containing the complexes as active ingredients | Newport Pharmaceuticals International, Inc. (US) | 1980-04-02 | — | — | EP | disclosed |