Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 6/20 | 0.57 |
| ▸ | POLA1 | P09884 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732874 | 0.88 | XDH (0.52) | XDHPOLA1HTTNCOA1SMN1; SMN2 | |
| SCHEMBL27762591 | 0.86 | XDH (0.50) | XDHPOLA1HTTNCOA1SMN1; SMN2 | |
| SCHEMBL9059986 | 0.84 | XDH (0.55) | XDHPOLA1HTTNCOA1SMN1; SMN2 | |
| SCHEMBL28237493 | 0.80 | PNP (0.46) | XDHPOLA1PNPPDE5AGDA | |
| SCHEMBL29450710 | 0.79 | XDH (0.44) | XDHPOLA1PNPPDE5AGDA | |
| SCHEMBL11270403 | 0.78 | XDH (0.62) | XDHPOLA1PNPPDE5ACDK1 | |
| SCHEMBL716338 | 0.78 | XDH (0.42) | XDHPOLA1HTTNCOA1SMN1; SMN2 | |
| SCHEMBL7680703 | 0.77 | XDH (0.60) | XDHPOLA1PNPPDE5AGDA | |
| SCHEMBL595204 | 0.76 | PNP (0.57) | XDHPNPGDA | |
| Hydrochloric Acid SCHEMBL17186358 | 0.75 | PNP (0.56) | XDHPNPGDA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806425-B1 | An improved regiospecific process for synthesis of acyclic nucleosides | LUPIN LAB LTD (IN) | 2001-08-29 | — | — | EP | disclosed |
| US-6043364-A | HEATING THE ISOMER IN AN ALKYLATING AGENT IN ABSENCE OF ACID CATALYST AND SOLVENT | LUPIN LABORATORIES LIMITED (IN) | 2000-03-28 | — | — | US | disclosed |
| EP-0976751-A1 | A process for the isomerisation of an N-7 isomer into an N-9 isomer useful in the synthesis of acyclic nucleosides | LUPIN LABORATORIES LIMITED (IN) | 2000-02-02 | — | — | EP | disclosed |
| US-5821367-A | REACTING A DIACYLGUANINE AND AN ALKYLATING AGENT IN THE ABSENCE OF AN ACID CATALYST AND A SOLVENT | LUPIN LABORATORIES LIMITED (IN) | 1998-10-13 | — | — | US | disclosed |
| EP-0806425-A1 | An improved regiospecific process for synthesis of acyclic nucleosides | LUPIN LABORATORIES LIMITED (IN) | 1997-11-12 | — | — | EP | disclosed |
| EP-0806425-A1 | An improved regiospecific process for synthesis of acyclic nucleosides | LUPIN LABORATORIES LIMITED (IN) | 1997-11-12 | — | — | EP | disclosed |
| US-4146715-A | ANTIVIRAL AGENTS | BURROUGHS WELLCOME CO. (US) | 1979-03-27 | — | — | US | disclosed |