SCHEMBL11270788

SCHEMBL11270788

COC(=O)CN(C(=O)CSC(=O)CC(C)C)c1c(C)ccc(Br)c1C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.31
MLYCD O95822 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11274383 0.91 RAB9A (0.33) CYP1A2CYP3A4CYP2C9CYP2C19HPGD
SCHEMBL11281203 0.88 RAB9A (0.35) HPGDRAB9A
SCHEMBL11292883 0.88 CYP1A2 (0.32) CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL11276489 0.87 RAB9A (0.38) RAB9AMLYCD
SCHEMBL11273473 0.87 MLYCD (0.33) HPGDRAB9AMLYCD
SCHEMBL11279572 0.87 ALDH1A1 (0.35) HPGDRAB9A
SCHEMBL11275086 0.86 RAB9A (0.32) HPGDRAB9A
SCHEMBL11278423 0.85 HDAC6 (0.34) CYP1A2CYP3A4CYP2C9CYP2C19HPGD
SCHEMBL11266992 0.85 RAB9A (0.34) HPGDRAB9A
SCHEMBL11275884 0.85 RAB9A (0.31) RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4313957-A Pesticidal sulfur containing amides derived from aniline and the method of preparation thereof RHONE-POULENC AGROCHIMIE (FR) 1982-02-02 US disclosed