Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | MMP7 | P09237 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | MMP14 | P50281 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2070966 | 0.85 | KMT2A (0.60) | KMT2AHSD11B1POLBMMP1MMP2 | |
| SCHEMBL7922108 | 0.83 | KMT2A (0.62) | KMT2AHSD11B1POLBMMP1MMP2 | |
| SCHEMBL3651298 | 0.80 | HSD11B1 (0.66) | KMT2AHSD11B1POLBMMP2MMP7 | |
| SCHEMBL2069911 | 0.79 | ALDH1A1 (0.69) | KMT2AHSD11B1POLBMMP1MMP2 | |
| SCHEMBL7321453 | 0.78 | POLB (0.66) | KMT2AHSD11B1POLBMMP2MMP7 | |
| SCHEMBL27517526 | 0.78 | CA12 (0.79) | KMT2APOLBMMP1MMP2MMP3 | |
| SCHEMBL11260658 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL3899884 | 0.76 | KMT2A (0.68) | KMT2AHSD11B1POLBMMP1MMP2 | |
| Water SCHEMBL15643605 | 0.76 | ALDH1A1 (0.65) | KMT2AHSD11B1POLBMMP1MMP2 | |
| SCHEMBL270706 | 0.76 | MMP2 (0.77) | KMT2AHSD11B1POLBMMP2MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329363-A | Substituted mercapto acid amides and their use | MERCK & CO., INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4216160-A | IMMUNOREGULANTS FOR CORRECTING AN INBALANCE OF IMMUNE HOMEOSTASIS | MERCK & CO., INC. (US) | 1980-08-05 | — | — | US | disclosed |