4-Methoxycinnamic Acid

4-Methoxycinnamic Acid

SCHEMBL11270862

CCCCC(CC)C(=O)OC(=O)C=Cc1ccc(OC)cc1.COc1ccc(C=CC(=O)O)cc1

nearest known ligand 0.62

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.62
THRB P10828 1/20 0.56
ATM Q13315 1/20 0.56
TAS1R3 Q7RTX0 4/20 0.54
TAS1R1 Q7RTX1 4/20 0.54
LMNA P02545 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
MAPT P10636 1/20 0.45
GSK3B P49841 1/20 0.45
F3 P13726 1/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
GAA P10253 1/20 0.43
TRPM8 Q7Z2W7 1/20 0.43
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
PTGER4 P35408 1/20 0.42
PTGER3 P43115 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Methoxycinnamic Acid SCHEMBL28527848 0.87 THRB (0.62) TDP1THRBATMTAS1R3TAS1R1
4-Methoxycinnamic Acid SCHEMBL1463076 0.87 THRB (0.62) TDP1THRBATMTAS1R3TAS1R1
4-Methoxycinnamic Acid SCHEMBL28754626 0.85 TDP1 (0.54) TDP1THRBATMTAS1R3TAS1R1
SCHEMBL4945999 0.85 LMNA (0.49) TDP1TAS1R3TAS1R1LMNASMN1; SMN2
SCHEMBL21462607 0.85 LMNA (0.49) TDP1TAS1R3TAS1R1LMNASMN1; SMN2
4-Methoxycinnamic Acid SCHEMBL344148 0.83 TDP1 (0.55) TDP1THRBATMTAS1R3TAS1R1
4-Methoxycinnamic Acid SCHEMBL27805505 0.83 TDP1 (0.55) TDP1THRBATMTAS1R3TAS1R1
4-Methoxycinnamic Acid SCHEMBL4657863 0.83 TDP1 (0.55) TDP1THRBATMTAS1R3TAS1R1
4-Methoxycinnamic Acid SCHEMBL910634 0.82 TDP1 (0.62) TDP1THRBATMTAS1R3TAS1R1
SCHEMBL29855518 0.81 TDP1 (0.74) TDP1THRBATMTAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4322544-A TRIGLYCERIDE OBTAINED FROM TWO MOLES OF P-METHOXY CINNAMIC ACID AND ONE MOLE EACH FATTY ACID AND GLYCEROL; SUNSCREEN AGENTS TORAY INDUSTRIES, INC. (JP) 1982-03-30 US claimed
US-4322544-A TRIGLYCERIDE OBTAINED FROM TWO MOLES OF P-METHOXY CINNAMIC ACID AND ONE MOLE EACH FATTY ACID AND GLYCEROL; SUNSCREEN AGENTS TORAY INDUSTRIES, INC. (JP) 1982-03-30 US disclosed