4-Methoxycinnamic Acid

4-Methoxycinnamic Acid

SCHEMBL1463076

CCCCC(CC)C(=O)O.COc1ccc(C=CC(=O)O)cc1.COc1ccc(C=CC(=O)O)cc1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.62
ATM Q13315 1/20 0.62
TDP1 Q9NUW8 2/20 0.59
TAS1R3 Q7RTX0 4/20 0.56
TAS1R1 Q7RTX1 4/20 0.56
GSK3B P49841 2/20 0.50
CA2 P00918 1/20 0.50
MAPK1 P28482 1/20 0.50
F3 P13726 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
GRIK1 P39086 1/20 0.47
GRIK2 Q13002 1/20 0.47
TRPM8 Q7Z2W7 1/20 0.47
LMNA P02545 1/20 0.47
BACE1 P56817 1/20 0.47
PTGER4 P35408 1/20 0.46
PTGER3 P43115 1/20 0.46
PTGER2 P43116 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Methoxycinnamic Acid SCHEMBL28527848 1.00 THRB (0.62) THRBATMTDP1TAS1R3TAS1R1
4-Methoxycinnamic Acid SCHEMBL11270862 0.87 TDP1 (0.62) THRBATMTDP1TAS1R3TAS1R1
4-Methoxycinnamic Acid SCHEMBL910634 0.87 TDP1 (0.62) THRBATMTDP1TAS1R3TAS1R1
4-Methoxycinnamic Acid SCHEMBL4844856 0.86 THRB (0.46) THRBATMTDP1TAS1R3TAS1R1
Cinnamic Acid SCHEMBL28537905 0.85 MAPK1 (0.57) TDP1CA2MAPK1F3SMN1; SMN2
4-Methoxycinnamic Acid SCHEMBL28754626 0.85 TDP1 (0.54) THRBATMTDP1TAS1R3TAS1R1
4-Methoxycinnamic Acid SCHEMBL4657863 0.84 TDP1 (0.55) THRBATMTDP1TAS1R3TAS1R1
4-Methoxycinnamic Acid SCHEMBL344148 0.84 TDP1 (0.55) THRBATMTDP1TAS1R3TAS1R1
4-Methoxycinnamic Acid SCHEMBL27805505 0.84 TDP1 (0.55) THRBATMTDP1TAS1R3TAS1R1
2-Ethylhexanoic Acid SCHEMBL5969968 0.83 TDP1 (0.66) THRBATMTDP1TAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190299032-A1 Oil-In-Water Type Emulsion Cosmetic Composition SHISEIDO COMPANY, LTD. (JP) 2019-10-03 US disclosed
US-20180056096-A1 Oil-In-Water Type Emulsion Cosmetic Composition SHISEIDO CO., LTD. (JP) 2018-03-01 US disclosed
EP-1576943-B1 Cosmetic oil-in-water emulsion preparation SHISEIDO CO LTD (JP) 2011-08-31 EP disclosed
US-20110070173-A1 Oil-in-Water Type Emulsion Cosmetic Composition SHISEIDO CO., LTD. (JP) 2011-03-24 US disclosed
EP-1674106-A1 DIETETIC COMPOSITION Oryza Oil & Fat Chemical Co., Ltd (JP) 2006-06-28 EP disclosed
EP-1576943-A1 COSMETIC OIL-IN-WATER EMULSION PREPARATION Shiseido Co., Ltd. (JP) 2005-09-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190299032-A1 Oil-In-Water Type Emulsion Cosmetic Composition CD44, DSG1, CUTA THRB 4132/4885ATM 3594/4885TDP1 4371/4885
US-20110070173-A1 Oil-in-Water Type Emulsion Cosmetic Composition DSG1, CD44, SQLE THRB 3835/4885ATM 1527/4885TDP1 4133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.