Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044246 | 0.75 | ABHD16A (0.48) | MAPTSMN1; SMN2GAAKDM4ERAD52 | |
| SCHEMBL11272220 | 0.75 | MEN1 (0.60) | MAPTSMN1; SMN2GAAKDM4ERAD52 | |
| SCHEMBL9378668 | 0.65 | PPOX (0.56) | TDP1MEN1KMT2ANR1I2PPOX | |
| SCHEMBL30930979 | 0.64 | MAPT (0.46) | MAPTSMN1; SMN2GAAKDM4ERAD52 | |
| SCHEMBL17292935 | 0.64 | MAPT (0.44) | MAPTSMN1; SMN2GAAKDM4ERAD52 | |
| SCHEMBL20278384 | 0.64 | MAPT (0.46) | MAPTSMN1; SMN2GAAKDM4ERAD52 | |
| SCHEMBL11728537 | 0.62 | MAPT (0.44) | MAPTSMN1; SMN2GAAKDM4ERAD52 | |
| SCHEMBL19814419 | 0.62 | MAPT (0.39) | MAPTSMN1; SMN2GAAKDM4ERAD52 | |
| SCHEMBL31312874 | 0.61 | MAPT (0.64) | MAPTSMN1; SMN2GAAKDM4ERAD52 | |
| SCHEMBL854657 | 0.61 | MAPT (0.64) | MAPTSMN1; SMN2GAAKDM4ERAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003619-B1 | HETEROCYCLIC-SUBSTITUTED ANILIDE DERIVATIVES, A PROCESS FOR THEIR PREPARATION, HERBICIDAL COMPOSITIONS CONTAINING THEM AND A METHOD OF CONTROLLING UNDESIRED PLANT GROWTH USING THEM | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1982-05-05 | — | — | EP | disclosed |
| US-4174958-A | Anilide derivative herbicides | SHELL OIL COMPANY (US) | 1979-11-20 | — | — | US | disclosed |
| EP-0003619-A2 | Heterocyclic-substituted anilide derivatives, a process for their preparation, herbicidal compositions containing them and a method of controlling undesired plant growth using them | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1979-08-22 | — | — | EP | disclosed |