Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271259 | 0.90 | AKR1B1 (0.50) | MAPTRAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL11261990 | 0.86 | MAOB (0.44) | GPR35HPGDMAPTRAB9AKDM4E | |
| SCHEMBL11275408 | 0.84 | HPGD (0.45) | POLBHPGDMAPTRAB9AKDM4E | |
| SCHEMBL11274526 | 0.82 | MAPT (0.49) | GPR35POLBHPGDMAPTRAB9A | |
| SCHEMBL11269705 | 0.82 | MAPT (0.41) | MAPTRAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL11278936 | 0.80 | GPR35 (0.48) | GPR35HPGDMAPTRAB9AKDM4E | |
| SCHEMBL11270471 | 0.79 | GPR35 (0.43) | GPR35PTGS2HPGDMAPTRAB9A | |
| SCHEMBL11280577 | 0.79 | AKR1B1 (0.43) | HPGDMAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL9665289 | 0.79 | NPC1 (0.49) | POLBMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28437380 | 0.74 | NPC1 (0.50) | RAB9ANPC1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364956-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1982-12-21 | — | — | US | disclosed |