Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11282494 | 0.84 | CASP1 (0.41) | MAPTALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL11271259 | 0.82 | AKR1B1 (0.50) | MAPTALDH1A1MAOBSLC2A1KMT2A | |
| SCHEMBL11271239 | 0.82 | GPR35 (0.47) | MAPTALDH1A1SMN1; SMN2MAOBTP53 | |
| SCHEMBL11261990 | 0.79 | MAOB (0.44) | MAPTALDH1A1MAOBSLC2A1KMT2A | |
| SCHEMBL19357342 | 0.75 | ALDH1A1 (0.63) | MAPTALDH1A1SMN1; SMN2MAOALMNA | |
| SCHEMBL21656854 | 0.75 | ALDH1A1 (0.63) | MAPTALDH1A1SMN1; SMN2MAOALMNA | |
| SCHEMBL21656494 | 0.74 | MAPT (0.61) | MAPTALDH1A1SMN1; SMN2MAOALMNA | |
| SCHEMBL21628564 | 0.74 | ALDH1A1 (0.50) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL21628656 | 0.74 | ALDH1A1 (0.50) | MAPTALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL21628580 | 0.73 | ALDH1A1 (0.48) | MAPTALDH1A1SMN1; SMN2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364956-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1982-12-21 | — | — | US | disclosed |