Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271259 | 0.86 | AKR1B1 (0.50) | MAOBALDH1A1AKR1B1NPC1RAB9A | |
| SCHEMBL11271239 | 0.86 | GPR35 (0.47) | MAOBALDH1A1HPGDNPSR1AKR1B1 | |
| SCHEMBL11265196 | 0.84 | ALDH1A1 (0.42) | ALDH1A1HPGDNPSR1NPC1RAB9A | |
| SCHEMBL11269705 | 0.79 | MAPT (0.41) | MAOBALDH1A1AKR1B1NPC1RAB9A | |
| SCHEMBL11265843 | 0.79 | MAPT (0.43) | MAOBALDH1A1HPGDNPSR1AKR1B1 | |
| SCHEMBL11280577 | 0.76 | AKR1B1 (0.43) | MAOBALDH1A1HPGDNPSR1AKR1B1 | |
| SCHEMBL11275408 | 0.76 | HPGD (0.45) | MAOBALDH1A1HPGDNPSR1AKR1B1 | |
| SCHEMBL19357359 | 0.72 | CA12 (0.54) | ALDH1A1HPGDNPSR1NPC1RAB9A | |
| SCHEMBL28437380 | 0.72 | NPC1 (0.50) | MAOBAKR1B1NPC1RAB9AMEN1 | |
| SCHEMBL19357358 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HPGDNPSR1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4364956-A | ASTHMA | LILLY INDUSTRIES LIMITED (GB) | 1982-12-21 | — | — | US | disclosed |