Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.30 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.30 |
| ▸ | ATF1 | P18846 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127174 | 0.91 | — | — | |
| SCHEMBL1127066 | 0.89 | KDM4E (0.30) | KDM4E | |
| SCHEMBL1127164 | 0.88 | TSHR (0.34) | TSHRKDM4EMEN1KMT2A | |
| SCHEMBL1127526 | 0.79 | PDK1 (0.33) | ATF1NFKB1 | |
| SCHEMBL1127305 | 0.79 | KDM4E (0.30) | KDM4E | |
| SCHEMBL1127068 | 0.79 | RAB9A (0.34) | NPC1RAB9AMEN1KMT2ASHMT1 | |
| SCHEMBL1127118 | 0.78 | RAB9A (0.35) | NPC1RAB9AALDH1A1TSHRKDM4E | |
| SCHEMBL24760921 | 0.75 | ERCC5 (0.44) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL1127144 | 0.74 | AGTR1 (0.30) | ALDH1A1 | |
| SCHEMBL1127147 | 0.74 | AGTR1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282636-A2 | BENZENE SULFONAMIDE THIAZOLE AND OXAZOLE COMPOUNDS | GlaxoSmithKline LLC (US) | 2011-02-16 | — | — | EP | disclosed |