Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | CLK1 | P49759 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276985 | 0.77 | CA1 (0.34) | CA1CA2 | |
| SCHEMBL11260229 | 0.77 | HTR2A (0.39) | CA1CA2PNMTMAPT | |
| Hydrochloric Acid SCHEMBL11273176 | 0.77 | MAPT (0.35) | CA1CA2MAPT | |
| Hydrochloric Acid SCHEMBL11270222 | 0.75 | HTR2A (0.38) | CA1CA2PNMTMAPT | |
| Hydrochloric Acid SCHEMBL11269902 | 0.75 | HTR2C (0.38) | CA1CA2MAPT | |
| Hydrochloric Acid SCHEMBL11267162 | 0.75 | HTR2C (0.38) | CA1CA2MAPT | |
| SCHEMBL11273824 | 0.73 | HTR2A (0.43) | CA1CA2PNMTMAPT | |
| Hydrochloric Acid SCHEMBL11264015 | 0.73 | KIF11 (0.34) | MAPT | |
| SCHEMBL11264145 | 0.72 | KIF11 (0.37) | MAPT | |
| Hydrochloric Acid SCHEMBL11267326 | 0.71 | KIF11 (0.37) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | claimed |
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | disclosed |