Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | HTR2B | P41595 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11267326 | 0.99 | KIF11 (0.37) | KIF11SIGMAR1NISCHHTR1DCNR1 | |
| SCHEMBL11277787 | 0.92 | SIGMAR1 (0.39) | KIF11SIGMAR1NISCHHTR1DHTR2C | |
| Hydrochloric Acid SCHEMBL11273339 | 0.91 | SIGMAR1 (0.39) | KIF11SIGMAR1NISCHHTR1DHTR2C | |
| SCHEMBL11275856 | 0.89 | KIF11 (0.35) | KIF11NISCHKDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL11264015 | 0.87 | KIF11 (0.34) | KIF11KDM4EALDH1A1LMNATP53 | |
| SCHEMBL11275332 | 0.78 | MAPT (0.36) | KIF11HTR2CKDM4EALDH1A1GAA | |
| SCHEMBL11260229 | 0.77 | HTR2A (0.39) | HTR2CHTR2BKDM4EMAPTALOX15 | |
| SCHEMBL11276985 | 0.77 | CA1 (0.34) | — | |
| SCHEMBL11263563 | 0.77 | HTR2C (0.39) | HTR2CALDH1A1MAPTHTR2A | |
| Hydrochloric Acid SCHEMBL11273176 | 0.77 | MAPT (0.35) | KIF11HTR2CKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328238-A | ANTIDEPRESSANTS, ANTISECRETORY, AND ANTIULCER AGENTS | SANKYO COMPANY LIMITED (JP) | 1982-05-04 | — | — | US | disclosed |