Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 3/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzophenone SCHEMBL11269386 | 0.98 | TSHR (0.40) | TSHRLMNATDP1ESR1PTGS2 | |
| Benzophenone SCHEMBL11274446 | 0.96 | TSHR (0.42) | TSHRLMNAESR1PTGS2CYP2D6 | |
| Benzophenone SCHEMBL11268574 | 0.90 | TDP1 (0.41) | LMNATDP1ESR1CNR2CYP2D6 | |
| Benzophenone SCHEMBL11266176 | 0.86 | SMN1; SMN2 (0.37) | TSHRLMNATDP1ESR1CYP2D6 | |
| Benzophenone SCHEMBL11265470 | 0.86 | SCN1A (0.35) | TSHRLMNATDP1ESR1CNR2 | |
| Benzophenone SCHEMBL11258100 | 0.85 | ABCB11 (0.36) | TSHRLMNATDP1ESR1CNR2 | |
| Benzophenone SCHEMBL11257262 | 0.85 | ABCB11 (0.36) | TSHRLMNATDP1ESR1CNR2 | |
| SCHEMBL11271773 | 0.85 | PTGS2 (0.46) | TSHRLMNAPTGS2CYP3A4THPO | |
| Methane SCHEMBL11292355 | 0.85 | MEN1 (0.39) | TSHRLMNAESR1CYP2D6CYP3A4 | |
| Benzophenone SCHEMBL11260403 | 0.84 | ABCB11 (0.35) | LMNATDP1ESR1CNR2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |