Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzophenone SCHEMBL11268574 | 0.96 | TDP1 (0.41) | SMN1; SMN2CYP1A2CYP2D6HPGDCYP2C19 | |
| Benzophenone SCHEMBL11264653 | 0.90 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AALDH1A1TSHR | |
| Benzophenone SCHEMBL11274446 | 0.90 | TSHR (0.42) | SMN1; SMN2CYP1A2CYP2D6HPGDCYP2C19 | |
| Benzophenone SCHEMBL11271133 | 0.89 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP1A2CYP2D6HPGDCYP2C19 | |
| Benzophenone SCHEMBL11269386 | 0.86 | TSHR (0.40) | SMN1; SMN2CYP1A2CYP2D6HPGDCYP2C19 | |
| Benzophenone SCHEMBL11271776 | 0.86 | TSHR (0.40) | SMN1; SMN2CYP1A2CYP2D6LMNATDP1 | |
| Benzophenone SCHEMBL11258074 | 0.86 | ABCB11 (0.49) | SMN1; SMN2CYP2D6LMNATDP1MEN1 | |
| SCHEMBL11266172 | 0.84 | PTGS2 (0.52) | SMN1; SMN2HPGDLMNAALDH1A1 | |
| Benzophenone SCHEMBL11260160 | 0.83 | SLC6A2 (0.35) | CYP1A2CYP2D6HPGDCYP2C19LMNA | |
| Benzophenone SCHEMBL11255134 | 0.83 | CYP2D6 (0.37) | CYP1A2CYP2D6CYP2C19LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362738-A | ANTIINFLAMMATORIES | DR. KARL THOMAE GMBH (DE) | 1982-12-07 | — | — | US | disclosed |